After surviving a brilliantly plotted murder attempt, the richest man in San Francisco is looking to hire the best protection money can buy. Enter Matt Jensen, who, for the princely sum of $5000, agrees to escort millionaire John Gillespie and his very fetching daughter on a railway journey from Frisco to Chicago. There's just one catch: the world's deadliest killers are coming along for the ride. In Provo, Utah, a knife-wielding assassin leads Jensen on a life-or-death chase across the top of the train. In Cheyenne, Wyoming, a ruthless pair of hired guns climb on board, ready to kill anyone who gets in their way. And in Omaha, Nebraska, three more cutthroats join the party. It doesn't take Matt Jensen long to realize this is no ordinary job. It's a one-way ticket to hell.