Cloning

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Cloning

Title:

Cloning

ISBN:

9781622755769

Edition:

First edition.

Physical Description:

xii, 164 pages : color illustrations ; 24 cm.

Series:

Biotechnology revolution.

Contents:

Cloning defined and major developments in the history of cloning -- Gene cloning, DNA analysis, and gene sequencing -- An overview of animal and plant reproduction processes -- Reproductive cloning and genetic engineering -- Therapeutic cloning -- Ethical and moral issues.

Subject Term:

Added Author:

Local Subject:

Teen nonfiction collection.

Holds:

Available:*

Library	Call Number	Status
Searching... Hardwood Creek Library (Forest Lake)	TEEN 660.65 CLO	Searching... Unknown
Searching... R.H. Stafford Library (Woodbury)	TEEN 660.65 CLO	Searching... Unknown

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Summary

Since the early 20th century, when Hans Spemann first twinned salamander embryos, scientists have made astounding progress in the science and technology of cloning. They have now developed the means to apply cloning in research, agriculture, and medicine. With advancements in cloning techniques for stem cell research, scientists have been able to explore human diseases at a cellular level, attempting to better understand the cellular mechanisms involved in disease. Readers explore the history, science, applications, and ethical issues of cloning. Sidebars profile pioneers in the field, including John Bertrand Gurdon, Ian Wilmut, Shinya Yamanaka, and James Thomson.

Ian Wilmut (1997)

Introduction	p. vi
Chapter 1 Cloning Defined and Major Developments in the History of Cloning	p. 1
Cloning In Nature	p. 2
Natural Cloning Processes in Humans	p. 3
Natural Cloning Processes in Plants	p. 5
Regeneration	p. 6
Artificial Cloning	p. 7
Early Cloning Experiments	p. 10
Sir John Bertrand Gurdon	p. 12
The Development Of Recombinant DNA Technology	p. 14
The First Cloned Mammals	p. 18
Cloning Experiments With Human Embryos	p. 23
Sir Ian Wilmut	p. 23
Education And Cryopreservation Research	p. 24
Genetic Engineering and Cloning Research	p. 26
Later Career	p. 31
Developments After Dolly	p. 32
A New Kind Of Stem Cell	p. 33
Shinya Yamanaka	p. 34
Chapter 2 Gene Cloning, DNA Analysis, and Gene Sequencing	p. 37
Gene Cloning	p. 38
Creating the Clone	p. 39
Isolating the Clone	p. 45
DNA Sequencing	p. 46
Uses of DNA Sequencing	p. 46
Methods of DNA Sequencing	p. 47
Paul Berg	p. 49
In Vitro Mutagenesis	p. 50
Gene Cloning and Genetically Modified Organisms	p. 52
Reverse Genetics	p. 54
Diagnostics	p. 54
Protein Manufacture	p. 55
Genomics	p. 57
Sequencing and Analysis of Genomes	p. 58
Genomics Applications	p. 59
Chapter 3 An Overview of Animal and Plant Reproduction Processes	p. 62
Reproductive Systems of Invertebrates	p. 64
Reproductive Systems of Vertebrates	p. 65
Parthenogenesis	p. 66
The Testes	p. 68
The Ovaries	p. 69
Ovulation	p. 71
Reproduction in Plants	p. 73
Early Development and Cell Differentiation	p. 77
Chapter 4 Reproductive Cloning and Genetic Engineering	p. 82
Dolly, the First Clone of an Adult Mammal	p. 83
Somatic Cell Nuclear Transfer	p. 87
Frozen Ark	p. 89
Genetically Modified Organisms	p. 90
Gmos in Agriculture	p. 91
Gmos in Medicine and Research	p. 94
Pharming	p. 96
Role of Gmos in Environmental Management	p. 98
De-Extinction	p. 99
The Commercialization of Gmos	p. 103
Chapter 5 Therapeutic Cloning	p. 106
Stem Cells From Human Embryos	p. 107
Regenerative Medicine and Stem Cells	p. 109
Hwanng Woo-Sur	p. 110
Cell and Bioartifical Tissue Transplantation	p. 113
Regeneration Using Stem Cells	p. 116
James Thomason	p. 118
Tissue Scaffolds and Soluble Repaid Factors	p. 120
Replacing Diseased Tissue	p. 124
Therapeutic Cloning and Gene Therapy	p. 126
Chapter 6 Ethical and Moral Issues	p. 129
Reproductive Cloning Of Humans	p. 131
The Uses and Ethics of Cloning	p. 134
The Use Of Human Embryos For Stem Cell Research	p. 141
Ethical And Social Issues: Gmos, De-Extinction, And Gene Therapy	p. 148
Sociopolitics Relevance of GMOS	p. 148
Ehtical Consideration of De-Extinction	p. 149
Concerns Related of therapejtic Cloning for Gene Therapy	p. 152
Conclusion	p. 153
Glossary	p. 156
Bibliography	p. 159
Index	p. 161

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